According to recent estimates, approximately 970 million people worldwide suffer from mental illness. Over 284 million individuals in the world suffer from anxiety disorders, 264 million from depression, 45 million from bipolar illness, 20 million from schizophrenia, and more than 50 million from dementia. Anxiety disorders are the most frequent mental ailment, affecting about 4% of the world’s population. Anxiety disorders have a high prevalence rate, and they also account for a significant portion of the costs associated with their treatment. These horrifying statistics are drawing experts’ attention to pharmacotherapeutic techniques for treating modernization-related problems. Medicinal chemists have looked at a variety of chemicals to prevent anxiety disorders, but there is still a lot more work to be done in this field. The high systemic toxicity of synthetic medications (barbiturates, benzodiazepines, and others) has expedited the quest for innovative natural compounds that can treat anxiety disorders and are less or non-toxic to humans. ScienceDirect, SciFinder, Chemical Abstracts, PubMed, Dr. Dukes Phytochemical & Ethnobotany, InteliHealth, CIMER, and other databases were used to compile the current review. The current review focuses on the botanical name, common name, part/extract/isolated phytoconstituent utilised, dosage, mechanism of action, animal models/clinical parameters in humans, and patented formulations of numerous plants used for the treatment of anxiety disorders.

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